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The AIDS/HIV portal covers current research in AIDS and HIV including new antiretroviral therapy, virus structure, and several other areas important to dealing with this formidable opponent.
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Antibodies are essential components of the immune system and they have also emerged as an essential research tool due to their specific binding to proteins. This portal looks at basic research into antibody function as well as research applications.
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One of our most popular portals, the apoptosis portal covers recent research into caspases, cell death mechanisms, and peripheral pathways involved in this important process.
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The asthma portal investigates the basic science and clinical implications of this increasingly common disorder.
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The atrial fibrillation portal investigates the basic science and clinical implications of this common cardiac disorder. New therapies are an important focus.
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The avian flu portal attempts to aggregate the sparse information available about this emerging threat. The biology of influenza A is also dealt with in this portal.
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The bioinformatics portal compiles information about the latest research in bio-computing, databases, and software.
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Biomarkers are used as indicators of disease progress and this portal explores the latest research and labs that explore these important disease markers.
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This portal covers all common brain tumors including gliomas, astrocytomas, glioblastomas, and other cerebral tumors.
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C. elegans is an important organism in molecular biology. It is one of the few organisms that is almost completely understood and this portal explores this influential model organism.
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Cancer is the most formidable medical foe in history. This portal examines clinical research as well as basic research into the mechanisms of cancer and cancer treatment.
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This portal covers all phases of the cell cycle and explores the implications of the the cell cycle on disease.
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Both the basic science and public health implications of cholesterol is addressed in this portal. All lipoproteins are explored including lipoprotein-interacting factors.
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Some of the areas of complementary and alternative medicine covered by this portal include acupuncture, medicinal herbs, massage, biofeedback, yoga, and much more.
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All known cytokines are explored in this portal including interferons, interleukins, chemokines, and the non-immunological cytokines erythropoetin and thrombopoetin.
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The cytoskeleton is the subject of this portal. Cytoskeletal proteins covered include actin/microfilaments, intermediate filaments, and microtubules. Proteins that interact with the cytoskeleton are also addressed.
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This portal covers both the basic science and clinical aspects of diabetes.
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All forms of drug metabolism are considered in this portal. Special attention is given to the cytochrome P450s and their role in drug oxidation.
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The epigenetics portal deals with epigenetic phenomena including DNA methylation, genomic imprinting, paramutations, histone modifications and much more.
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The evolution portal explores the origin of species including mechanisms of evolution, natural selection and ways in which gradual change sculpted all species today.
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The free radical portal deals with current research into various oxidative species including the superoxide anion and the hydroxyl radical to name a few. Coverage also includes enzymes such as superoxide dismutase, catalase, and other enzymes important in establishing the redox balance. Antioxidants are also covered.
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Current research in gene therapy is the focus of this portal. Special attention is given to gene transfer technology and the role it plays in the treatment of disease.
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From microglia to macroglia, the basic science behind the all important neuronal glia cell-type is the subject of this portal.
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Both G proteins and G-protein coupled receptors are investigated in this portal. All GPCRs are covered here as well as the large heterotrimeric G proteins and their smaller cousins, the GTPases.
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All major growth factor families such as TGF-beta, BMP, neurotrophins, FGF and many others are discussed in this portal.
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All major heat shock proteins are discussed including both those in prokaryotes and those in eukaryotes.
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The role of high-throughput-screening in the drug discovery process in the major focus of this portal. Microarrays are also a major focus of this portal.
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Our oldest and most popular portal. This portal formed the structure upon which all other portals were built. Ion channels, patch clamp, and electrophysiology are the major focus.
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Knockout mice and other transgenic animals (and plants) are the focus of this portal.
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The malaria portal explores the basic science, clinical implications, and serious world issues related to this forgotten disease.
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All about mesothelioma, a deadly asbestos-related cancer. While the majority of coverage is legal and medical, there is some discussion of basic science as well.
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Micro-bugs explores recent discoveries in microbiology and covers all forms of bacteria and bacteria-related disease.
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One of our most popular portals, this portal covers all aspects of mitochondria research. Coverage includes their basic role in cellular respiration as well as their role in some rare, but devastating diseases.
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Basic science and clinical aspects of myocardial ischemia are the focus of this portal.
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Medicine on a nano-scale is the subject of this popular portal.
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The role of nitric oxide as an important cellular signaling molecule is the focus of this portal.
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This portal investigates nucleases, enzymes capable of cleaving the phosphodiester bonds between nucleic acids.
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A popular companion to our protein kinase research portal, this portal investigates phosphatases, enzymes that remove phosphates from other molecules and proteins.
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The subjects of the prostaglandin portal include all the prostanoid derivatives as well as enzymes important in their synthesis and regulation.
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Proteins that chew up other proteins is the topic of the protease portal.
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This portal covers a lot of ground. All protein kinases are covered in this portal, with the majority of focus being basic science. This portal is complementary to our protein phosphatase portal.
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The protein trafficking portal covers protein sorting, trafficking, folding, and degradation.
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The proteomics portal covers anything related to the identification of protein function as well as other 'omes' including the metabolome, secretome, and many others.
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This portal covers both real time time/quantitative PCR as well as reverse-transcriptase PCR.
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RNA interference is the topic of this portal. Areas of interest include the role of RNA interference in drug discovery and basic science. siRNA synthesis is also an important focus.
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Microgravity, space flight, and astronaut health are a few topics covered in this portal. Anything related to space medicine is dealt with in detail.
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Both embryonic and adult-derived stem cells are discussed here.
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Basic science and clinical implications of strokes are discussed here.
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Ventricular fibrillation, the most acute and serious cardiovascular complication is discussed here. Basic science and clinical implications are the focus.
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Virus Hunters is a portal that covers the latest advancements in virology including retroviruses, and the latest viral threats.
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Yeast is an important model organism in molecular biology. This portal examines all the different species of yeast and the latest discoveries made with this important research tool.
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